Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 10/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513258 | 0.82 | PARP10 (0.43) | KDRPDGFRBMEN1KMT2A | |
| SCHEMBL28672695 | 0.77 | NOD2 (0.68) | NOD2NOD1KDRPDGFRBF10 | |
| SCHEMBL8360588 | 0.74 | KDR (0.51) | KDRPDGFRBMEN1KMT2ASLC9A1 | |
| SCHEMBL31122079 | 0.74 | KDR (0.51) | KDRPDGFRBMEN1KMT2ASLC9A1 | |
| SCHEMBL4056238 | 0.73 | NOD2 (0.50) | NOD2NOD1NR1H2MEN1KMT2A | |
| Benzene SCHEMBL28136154 | 0.72 | KDR (0.50) | KDRPDGFRBMEN1KMT2ASLC9A1 | |
| Hydrochloric Acid SCHEMBL28136871 | 0.72 | KDR (0.50) | KDRPDGFRBMEN1KMT2ASLC9A1 | |
| SCHEMBL31315441 | 0.72 | KDR (0.43) | KDRPDGFRB | |
| SCHEMBL8679771 | 0.72 | KDR (0.49) | KDRPDGFRBSLC9A1 | |
| SCHEMBL28615205 | 0.71 | NOD2 (0.51) | NOD2NOD1F10NR1H2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791537-A1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE I | Aventis Pharmaceuticals, Inc. (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006023590-A1 | 3-ARYLTHIOINDOLE-2-CARBOXAMIDE DERIVATIVES AND ANALOGS THEREOF AS INHIBITORS OF CASEIN KINASE Iϵ | AVENTIS PHARMACEUTICALS INC. (US) | 2006-03-02 | — | — | WO | disclosed |