Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613208 | 0.87 | TSHR (0.47) | NOD2NOD1L3MBTL1MEN1KMT2A | |
| SCHEMBL28615203 | 0.84 | L3MBTL1 (0.47) | NOD2NOD1L3MBTL1NR1H2MEN1 | |
| SCHEMBL3972260 | 0.84 | NOD2 (0.53) | NOD2NOD1L3MBTL1NR1H2MEN1 | |
| SCHEMBL6706688 | 0.81 | NOD2 (0.51) | NOD2NOD1L3MBTL1NR1H2MEN1 | |
| SCHEMBL4056238 | 0.80 | NOD2 (0.50) | NOD2NOD1L3MBTL1NR1H2MEN1 | |
| SCHEMBL6988991 | 0.80 | NOD2 (0.71) | NOD2NOD1L3MBTL1MEN1KMT2A | |
| SCHEMBL28628548 | 0.80 | ALDH1A1 (0.49) | NOD2NOD1L3MBTL1NR1H2MEN1 | |
| SCHEMBL4554717 | 0.80 | NR1H2 (0.60) | NR1H2 | |
| SCHEMBL5136650 | 0.79 | NOD2 (0.55) | NOD2NOD1L3MBTL1MEN1KMT2A | |
| SCHEMBL6072599 | 0.78 | POLB (0.50) | NOD2NOD1L3MBTL1NR1H2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530335-B | Indole compound and preparation method and application thereof | 华南农业大学 | 2021-08-31 | — | — | CN | disclosed |