Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679295 | 0.85 | CYP2D6 (0.43) | L3MBTL1ALDH1A1TDP1MMP1MMP2 | |
| SCHEMBL9853199 | 0.81 | MTNR1A (0.50) | MTNR1AMTNR1BMAPK1TSHRUSP2 | |
| SCHEMBL12341335 | 0.80 | EPHX1 (0.49) | TSHR | |
| SCHEMBL20749852 | 0.80 | MMP1 (0.38) | KDM4EL3MBTL1ALDH1A1TDP1MMP1 | |
| Hydrochloric Acid SCHEMBL30512137 | 0.80 | CACNA2D1 (0.46) | MTNR1AMTNR1BMAPK1TSHRUSP2 | |
| SCHEMBL26478811 | 0.79 | ZDHHC20 (0.42) | MAPK1TSHRALDH1A1TDP1MMP1 | |
| SCHEMBL18378814 | 0.79 | MMP1 (0.46) | ALDH1A1TDP1MMP1MMP2MMP3 | |
| SCHEMBL22340363 | 0.78 | MMP1 (0.37) | KDM4EALDH1A1TDP1MMP1MMP2 | |
| SCHEMBL20954435 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BMAPK1TSHRUSP2 | |
| SCHEMBL12523122 | 0.78 | MAPK1 (0.44) | MTNR1AMTNR1BMAPK1TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |