Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.91 | LMNA (0.73) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| Benzyl Phenethylcarbamate SCHEMBL6392045 | 0.86 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| Benzyl Phenethylcarbamate SCHEMBL27338403 | 0.85 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL6554125 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL10444759 | 0.85 | PLAU (0.60) | LMNASMN1; SMN2HTTTGM2KEAP1 | |
| SCHEMBL25334836 | 0.83 | HTT (0.56) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL9487307 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL160715 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL13884390 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL8802503 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447375-A | Guanidine compound, preparation method and application thereof | 中国医学科学院药物研究所 | 2024-01-26 | — | — | CN | disclosed |
| US-20200079808-A1 | GLYCOPOLYMERS SEQUESTERING CARBOHYDRATE-BINDING PROTEINS | POLYNEURON PHARMACEUTICALS AG (CH) | 2020-03-12 | — | — | US | disclosed |
| WO-2011149827-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-12-01 | — | — | WO | disclosed |
| US-RE39576-E1 | Enzyme inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-17 | — | — | US | disclosed |
| EP-0957087-B1 | Intermediates useful in the preparation of enzyme inhibitors | WELLCOME FOUND (GB) | 2002-12-04 | — | — | EP | disclosed |
| EP-0765308-B1 | ENZYME INHIBITORS | WELLCOME FOUND (GB) | 2000-04-05 | — | — | EP | disclosed |
| EP-0957087-A2 | Enzyme inhibitors | THE WELLCOME FOUNDATION LIMITED (GB) | 1999-11-17 | — | — | EP | disclosed |
| US-5889056-A | OF NITRIC OXIDE SYNTHASE; HYPOTENSIVE AGENT, ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | GLAXO WELLSOME INC. (US) | 1999-03-30 | — | — | US | disclosed |
| EP-0765308-A1 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995034534-A1 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079808-A1 | GLYCOPOLYMERS SEQUESTERING CARBOHYDRATE-BINDING PROTEINS | LGALS3BP, LGALS3, LGALS1 | LMNA 1436/4885SMN1; SMN2 4584/4885HTT 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.