Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 10/20 | 0.83 |
| ▸ | F12 | P00748 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235618 | 0.92 | PRMT1 (0.84) | PRMT1F2F10 | |
| SCHEMBL12711172 | 0.79 | PRMT1 (0.65) | PRMT1F2F10 | |
| SCHEMBL17084488 | 0.77 | PRMT1 (0.88) | PRMT1F2PLGPLAUPRSS1 | |
| SCHEMBL7979972 | 0.77 | PRMT1 (0.88) | PRMT1F2PLGPLAUPRSS1 | |
| SCHEMBL8815310 | 0.77 | PRMT1 (0.88) | PRMT1F2PLGPLAUPRSS1 | |
| SCHEMBL12412056 | 0.74 | PRMT1 (1.00) | PRMT1F2F10 | |
| SCHEMBL20184756 | 0.74 | PRMT1 (1.00) | PRMT1F12F2PLGPLAU | |
| SCHEMBL5516771 | 0.73 | PRMT1 (0.78) | PRMT1F12PLGPLAUKLK1 | |
| SCHEMBL8229718 | 0.71 | PRMT1 (0.89) | PRMT1F2PLGPLAUPRSS1 | |
| SCHEMBL20184755 | 0.71 | PRMT1 (1.00) | PRMT1F2PLGPLAUKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691859-B2 | Broad spectrum antibacterial compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2014-04-08 | — | — | US | disclosed |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | MPO, CAT, LPO | PRMT1 2817/4885F12 3188/4885F2 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.