SCHEMBL5514099

SCHEMBL5514099

CNc1c(F)ccc(O)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.39
KIF5B P33176 2/20 0.39
KDR P35968 2/20 0.39
MEP1B Q16820 1/20 0.38
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
ADRA2A P08913 4/20 0.34
ADRA2B P18089 4/20 0.34
ADRA2C P18825 4/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
ADRA1A P35348 1/20 0.34
IDO1 P14902 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
HSD17B1 P14061 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5512551 0.82 CA3 (0.34) RETKIF5BKDRMEP1BCA3
SCHEMBL6137822 0.80 CES2 (0.32) ADRA2AADRA2BADRA2C
SCHEMBL5513242 0.79 ESR1 (0.40) RETKIF5BKDRMEP1BCA3
SCHEMBL5517348 0.77 ADRA2A (0.36) RETKIF5BKDRCA3CA6
SCHEMBL5511699 0.77 TSHR (0.38) ADRA2AADRA2BADRA2C
SCHEMBL5516451 0.76 ADRA2A (0.36) MEP1BCA3CA6CA5ACA9
Phenol SCHEMBL27639114 0.75 CA12 (0.42) CA3CA5ACA9CA14CA5B
SCHEMBL5513312 0.74 BRAF (0.32) IDO1
SCHEMBL25706571 0.74 RAPGEF4 (0.34)
SCHEMBL5518501 0.74 RET (0.35) RETKIF5BKDRMEP1BCA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed