SCHEMBL5515978

SCHEMBL5515978

CNc1cc(F)c(F)c(NC)c1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1637217 0.85 RAPGEF4 (0.46) RAPGEF4
SCHEMBL1638888 0.78 CES2 (0.38) RAPGEF4
SCHEMBL14528479 0.76 RAPGEF4 (0.45) RAPGEF4
SCHEMBL5513274 0.74 RAPGEF4 (0.35) RAPGEF4
SCHEMBL5515607 0.74 ALDH1A1 (0.31)
SCHEMBL5517867 0.74 RAPGEF4 (0.35) RAPGEF4
SCHEMBL16838143 0.74 RAPGEF4 (0.35) RAPGEF4
SCHEMBL5511613 0.74 TAAR1 (0.35)
SCHEMBL5516191 0.72 HDAC1 (0.41) RAPGEF4
SCHEMBL5518604 0.72 RAPGEF4 (0.35) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed