Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 9/20 | 0.65 |
| ▸ | HEXA | P06865 | 5/20 | 0.53 |
| ▸ | HEXB | P07686 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12487635 | 0.79 | DHFR (1.00) | DHFRHEXAHEXBTP53CYP1A2 | |
| SCHEMBL5528016 | 0.79 | HEXA (0.72) | DHFRHEXAHEXBTP53CYP1A2 | |
| SCHEMBL12487396 | 0.74 | DHFR (1.00) | DHFRHEXAHEXBTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL12486624 | 0.73 | DHFR (1.00) | DHFRHEXAHEXBTP53CYP1A2 | |
| SCHEMBL12525588 | 0.73 | DHFR (0.85) | DHFRHEXAHEXBTP53CYP1A2 | |
| SCHEMBL12368248 | 0.70 | HEXA (1.00) | DHFRHEXAHEXBTP53CYP1A2 | |
| SCHEMBL9152649 | 0.68 | CYP3A4 (0.63) | RAB9ANPC1TP53CYP1A2GAA | |
| SCHEMBL6836988 | 0.68 | CYP3A4 (0.63) | RAB9ANPC1TP53CYP1A2GAA | |
| SCHEMBL17108413 | 0.68 | CYP3A4 (0.63) | RAB9ANPC1TP53CYP1A2GAA | |
| SCHEMBL5380417 | 0.67 | RAB9A (0.60) | RAB9ANPC1TP53CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135437-A1 | Modulation of neurodegenerative diseases | ALSGEN, INC. (US) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135437-A1 | Modulation of neurodegenerative diseases | SMN1; SMN2, SOD1, SOD3 | DHFR 1963/4885HEXA 123/4885HEXB 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.