Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NEK1 | Q96PY6 | 3/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505257 | 0.86 | ALDH1A1 (0.39) | KMT2AHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5511370 | 0.81 | RHEB (0.40) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL1854840 | 0.74 | KMT2A (0.66) | KMT2AMEN1MAPTPARP10CA1 | |
| SCHEMBL5574004 | 0.72 | KMT2A (0.39) | KMT2ANEK1POLB | |
| SCHEMBL22507148 | 0.71 | ACACB (0.58) | KMT2AMEN1MAPTPARP10CA1 | |
| SCHEMBL5266671 | 0.71 | POLB (0.41) | KMT2AMEN1MAPTNEK1CA1 | |
| SCHEMBL5509080 | 0.69 | PTPN5 (0.37) | MAPTKDM4EMAPK1 | |
| SCHEMBL5268671 | 0.68 | KDM4E (0.52) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL5502135 | 0.68 | KMT2A (0.45) | KMT2APARP10KDM4E | |
| SCHEMBL24515181 | 0.68 | CA1 (0.64) | KMT2AMEN1MAPTERN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |