Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271428 | 0.81 | MAPT (0.41) | PTPN5MAPTKDM4EPTPN1PPARD | |
| SCHEMBL5266914 | 0.81 | MAPT (0.41) | PTPN5MAPTKDM4EPTPN1PPARD | |
| SCHEMBL5505257 | 0.81 | ALDH1A1 (0.39) | LMNAACACBACACAMAPTKDM4E | |
| SCHEMBL5339470 | 0.81 | GPR35 (0.37) | PTPN5ACACBACACAMAPTKDM4E | |
| SCHEMBL5269766 | 0.79 | TOP2A (0.38) | PTPN5SCN8ASCN10APPARD | |
| SCHEMBL5270824 | 0.78 | PTPN1 (0.37) | PTPN5MAPTKDM4EPTPN1PPARD | |
| SCHEMBL5267628 | 0.78 | PPARD (0.39) | MAPTPTPN1PPARD | |
| SCHEMBL5268151 | 0.76 | MAPT (0.36) | PTPN5MAPTSCN8ASCN10APPARD | |
| SCHEMBL5508772 | 0.76 | MAPT (0.41) | LMNAACACBACACAMAPTKDM4E | |
| SCHEMBL5270354 | 0.74 | MAPT (0.49) | LMNAMAPTCYP3A4CYP3A5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |