Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NEK1 | Q96PY6 | 12/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507821 | 0.83 | ACACB (0.39) | KMT2ALMNAPOLBMCL1NEK1 | |
| SCHEMBL5266671 | 0.80 | POLB (0.41) | KMT2ALMNAPOLBNEK1 | |
| SCHEMBL5505357 | 0.78 | PDE10A (0.37) | LMNAMCL1 | |
| SCHEMBL5501032 | 0.77 | THRA (0.40) | KMT2ARXRARXRB | |
| SCHEMBL5502096 | 0.76 | BRD4 (0.39) | LMNA | |
| SCHEMBL5505257 | 0.76 | ALDH1A1 (0.39) | KMT2ALMNAPOLBNEK1 | |
| SCHEMBL5507785 | 0.73 | ALOX5 (0.42) | KMT2ALMNANEK1 | |
| SCHEMBL5518524 | 0.72 | KMT2A (0.39) | KMT2APOLBNEK1 | |
| SCHEMBL5272473 | 0.72 | MAPT (0.46) | KMT2ALMNAPOLBNEK1 | |
| SCHEMBL5267628 | 0.71 | PPARD (0.39) | KMT2APOLBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841736-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077367-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |