Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922847 | 0.85 | CA2 (0.50) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL12460558 | 0.84 | CA2 (0.42) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL18286659 | 0.83 | CA2 (0.43) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL9610772 | 0.82 | CA2 (0.48) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL106425 | 0.82 | CA2 (0.48) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL23602332 | 0.82 | CA2 (0.48) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL14036948 | 0.82 | CA2 (0.48) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL14929446 | 0.81 | CA2 (0.47) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL10167848 | 0.81 | CA2 (0.47) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 | |
| SCHEMBL12133986 | 0.80 | CA2 (0.51) | CA2ALDH1A1TMEM97SIGMAR1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |