SCHEMBL5519174

SCHEMBL5519174

OC(C1CCCCC1)C1CO1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EPHX1 P07099 2/20 0.34
SHBG P04278 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
MMP2 P08253 2/20 0.31
CA9 Q16790 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12517981 0.87
SCHEMBL1077444 0.78 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9254730 0.78 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT
SCHEMBL28204907 0.78 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT
SCHEMBL2712401 0.74 TP53 (0.46) TP53KDM4EGMNNLMNAMAPT
SCHEMBL4306422 0.74
SCHEMBL622244 0.74
SCHEMBL15352983 0.72 TSHR (0.45) TP53KDM4EGMNNLMNAMAPT
SCHEMBL9493197 0.72 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT
SCHEMBL8458992 0.72 TP53 (0.50) TP53KDM4EGMNNLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7230145-B2 Catalyst for producing both end-hydroxyl group-terminated diols, process for producing the catalyst, process for producing the diols by using the catalyst, and both end-hydroxyl group-terminated diols obtained by the process SHOWA DENKO K.K. (JP) 2007-06-12 US disclosed
US-20040236156-A1 Catalyst for producing both end-hydroxyl group-terminated diols, process for producing the catalyst, process for producing the diols by using the catalyst, and both end-hydroxyl group-terminated diols obtained by the process SHOWA DENKO K.K. 2004-11-25 US disclosed
US-20030119666-A1 Catalyst for producing both end-hydroxyl group-terminated diols, process for producing the catalyst, process for producing the diols by using the catalyst, and both end-hydroxyl group-terminated diols obtained by the process KADOWAKI YASUSHI (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236156-A1 Catalyst for producing both end-hydroxyl group-terminated diols, process for producing the catalyst, process for producing the diols by using the catalyst, and both end-hydroxyl group-terminated diols obtained by the process ADH1C, ADH1A, EPHX2 TP53 4164/4885KDM4E 513/4885GMNN 464/4885
US-20030119666-A1 Catalyst for producing both end-hydroxyl group-terminated diols, process for producing the catalyst, process for producing the diols by using the catalyst, and both end-hydroxyl group-terminated diols obtained by the process ADH1C, ADH1A, EPHX2 TP53 4146/4885KDM4E 545/4885GMNN 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.