Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710680 | 0.86 | HSD11B1 (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL5203373 | 0.79 | KMT2A (0.41) | ALDH1A1KDM4ENPC1HPGDL3MBTL1 | |
| SCHEMBL7524889 | 0.78 | CYP1A2 (0.44) | ALDH1A1KDM4ESMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL805428 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL16334247 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL10834448 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL12048608 | 0.73 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL12579144 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD | |
| SCHEMBL5660651 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4ESMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL4257786 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241770-B2 | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARMACEUTICALS GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| US-6951918-B2 | Peptidic procollagen C-proteinase inhibitors | SYNTEX (U.S.A.) LLC (US) | 2005-10-04 | — | — | US | disclosed |
| US-20050131004-A1 | Hydronopol derivatives as agonists on human ORL1 receptors | SOLVAY PHARMACEUTICALS GMBH. | 2005-06-16 | — | — | US | disclosed |
| US-6426402-B1 | RESPIRATORY SYSTEM DISORDERS; RHEUMATIC DISEASES | SYNTEX (U.S.A.) LLC | 2002-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131004-A1 | Hydronopol derivatives as agonists on human ORL1 receptors | OPRL1, ORMDL3, OGFRL1 | ALDH1A1 498/4885KDM4E 4873/4885SMN1; SMN2 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.