Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298664 | 0.85 | KIF11 (0.38) | KIF11CES2CA2ERN1AR | |
| SCHEMBL30368138 | 0.85 | KIF11 (0.38) | KIF11CES2CA2ERN1AR | |
| SCHEMBL23542366 | 0.85 | ALDH1A1 (0.42) | ALDH1A1CA1CA2LMNAHPGD | |
| SCHEMBL4542512 | 0.83 | KIF11 (0.36) | KIF11HSD17B1HSD17B2CES2CA2 | |
| SCHEMBL30368280 | 0.83 | KIF11 (0.36) | KIF11HSD17B1HSD17B2CES2CA2 | |
| SCHEMBL27846971 | 0.82 | PIM1 (0.36) | KIF11PIK3CAPIM1ADAMTS4ALDH1A1 | |
| SCHEMBL5515481 | 0.81 | KIF11 (0.35) | KIF11HSD17B1HSD17B2PIK3CACES2 | |
| SCHEMBL5508293 | 0.77 | GLA (0.34) | KIF11HSD17B1HSD17B2CES2ALDH1A1 | |
| SCHEMBL9367573 | 0.77 | KIF11 (0.33) | KIF11HSD17B1HSD17B2CES2TMPRSS4 | |
| SCHEMBL17341736 | 0.77 | PIM1 (0.43) | KIF11HSD17B1HSD17B2PIK3CACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |