SCHEMBL4542512

SCHEMBL4542512

Oc1ccc(C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.36
HSD17B1 P14061 3/20 0.34
HSD17B2 P37059 3/20 0.34
CA2 P00918 1/20 0.33
CES2 O00748 1/20 0.33
TMPRSS4 Q9NRS4 2/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
NQO2 P16083 1/20 0.31
AR P10275 3/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
DAO P14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30368280 1.00 KIF11 (0.36) KIF11HSD17B1HSD17B2CA2CES2
SCHEMBL5146822 0.87 NQO2 (0.37) KIF11HSD17B1HSD17B2CA2CES2
SCHEMBL5795608 0.84 POLB (0.36) KIF11CA2CES2ARDAO
SCHEMBL5515481 0.83 KIF11 (0.35) KIF11HSD17B1HSD17B2CES2TMPRSS4
SCHEMBL5519963 0.83 KIF11 (0.35) KIF11HSD17B1HSD17B2CA2CES2
SCHEMBL5515872 0.79 GLA (0.34) KIF11HSD17B1HSD17B2CES2TMPRSS4
SCHEMBL5508293 0.79 GLA (0.34) KIF11HSD17B1HSD17B2CES2TMPRSS4
SCHEMBL9367573 0.79 KIF11 (0.33) KIF11HSD17B1HSD17B2CES2TMPRSS4
SCHEMBL4891656 0.78 HSD17B1 (0.41) KIF11HSD17B1HSD17B2CA2AR
SCHEMBL7298664 0.77 KIF11 (0.38) KIF11CA2CES2ARDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4484407-A2 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2025-01-01 EP disclosed
CN-113631597-B Laminate, composition, and laminate-forming kit 富士胶片株式会社 2022-12-06 CN disclosed
US-11142636-B2 (Meth)acrylate compound, additive for optical resin, optical element, and optical device NIKON CORPORATION (JP) 2021-10-12 US disclosed
US-20190322857-A1 (METH)ACRYLATE COMPOUND, ADDITIVE FOR OPTICAL RESIN, OPTICAL ELEMENT, AND OPTICAL DEVICE NIKON CORPORATION (JP) 2019-10-24 US disclosed
WO-2012063972-A1 METHOD FOR COATING REACTOR SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-18 WO disclosed
EP-1325934-B1 Modified particles, carrier prepared therefrom, catalyst component for olefin polymerization prepared therefrom, catalyst for olefin polymerization prepared therefrom, and method for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2005-03-16 EP disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed