Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 5/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520443 | 1.00 | METAP2 (0.32) | METAP2BRS3P2RX4P2RX7SLC40A1 | |
| SCHEMBL1013917 | 0.88 | HTR6 (0.36) | METAP2BRS3P2RX4P2RX7CA1 | |
| SCHEMBL1013915 | 0.88 | HTR6 (0.36) | METAP2BRS3P2RX4P2RX7CA1 | |
| Hydrochloric Acid SCHEMBL1017421 | 0.87 | HTR6 (0.35) | METAP2BRS3P2RX4P2RX7CA1 | |
| Hydrochloric Acid SCHEMBL1017420 | 0.87 | HTR6 (0.35) | METAP2BRS3P2RX4P2RX7CA1 | |
| SCHEMBL13223273 | 0.84 | CA1 (0.42) | LMNACA1CA2 | |
| SCHEMBL5528853 | 0.78 | — | — | |
| SCHEMBL13792661 | 0.78 | KMT2A (0.46) | LMNACA1CA2 | |
| SCHEMBL14135672 | 0.78 | KMT2A (0.46) | LMNACA1CA2 | |
| SCHEMBL2805469 | 0.78 | PTPRC (0.38) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265281-A1 | Organic Compounds and Their Uses | COTTENS SYLVAIN | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265281-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | METAP2 1061/4885BRS3 3419/4885P2RX4 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.