SCHEMBL5520736

SCHEMBL5520736

CCCCCCCCCCCC(=O)C(O)CCOP(=O)([O-])OCC[N+](C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
ESR1 P03372 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
CDC25A P30304 1/20 0.62
AGTR1 P30556 1/20 0.62
AKT1 P31749 1/20 0.62
ADRA1A P35348 1/20 0.62
KCNH2 Q12809 1/20 0.62
PLA2G1B P04054 1/20 0.60
PLA2G2A P14555 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.57
NR5A2 O00482 1/20 0.57
NR5A1 Q13285 1/20 0.57
MAPT P10636 3/20 0.55
PLA2G10 O15496 1/20 0.55
MAPK1 P28482 4/20 0.54
MEN1 O00255 2/20 0.54
GMNN O75496 2/20 0.54
BLM P54132 2/20 0.54
KMT2A Q03164 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18210636 0.83 SMN1; SMN2 (0.61) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL9710185 0.83 SMN1; SMN2 (0.61) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL17962981 0.83 SMN1; SMN2 (0.61) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL8960305 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL9073605 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL15566127 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL6268031 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL1648522 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL5251441 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL2370673 0.80 LMNA (0.54) LMNAESR1ADORA3CDC25AAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070042030-A1 Preparation for the application of agents in mini-droplets IDEA AG (DE) 2007-02-22 US disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
EP-0935457-B1 PREPARATION FOR THE TRANSPORT OF AN ACTIVE SUBSTANCE ACROSS BARRIERS IDEA AG (DE) 2004-01-07 EP disclosed
US-6165500-A Preparation for the application of agents in mini-droplets IDEA AG (DE) 2000-12-26 US disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
EP-0406162-B1 PROCESS FOR THE PREPARATION OF A NANOEMULSION OF OILPARTICLES IN AN AQUEOUS PHASE Weder, Hans Georg, Prof. Dr. (CH) 1993-09-08 EP disclosed
US-5152923-A Mixing triglyceride or fatty acid ester and an amphoteric emulsifier to form alamellar liquid cyr stalline structure and subjecting to high pressure homogenizing Weder, Hans Georg (CH) 1992-10-06 US disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed
EP-0406162-A2 Process for the preparation of a nanoemulsion of oilparticles in an aqueous phase Weder, Hans Georg, Prof. Dr. (CH) 1991-01-02 EP disclosed
US-4619794-A Spontaneous preparation of small unilamellar liposomes CIBA-GEIGY CORPORATION (US) 1986-10-28 US disclosed
EP-0102324-A2 Lipids and surfactants in an aqueous medium CIBA-GEIGY AG (CH) 1984-03-07 EP disclosed
EP-0088046-A2 Lipids in the aqueous phase CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042030-A1 Preparation for the application of agents in mini-droplets FABP4, NPC1L1, LIPA LMNA 327/4885ESR1 4104/4885ADORA3 1717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.