SCHEMBL5520993

SCHEMBL5520993

O=C(O)CC(Oc1ccccc1C(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.47
KMT2A Q03164 2/20 0.47
PTK2B Q14289 1/20 0.47
KDM4E B2RXH2 9/20 0.46
HTT P42858 3/20 0.46
HSD17B10 Q99714 7/20 0.46
HPGD P15428 5/20 0.46
ESR1 P03372 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
TSHR P16473 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
BLM P54132 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
USP2 O75604 1/20 0.45
PDE3A Q14432 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212426 0.80 ALDH1A1 (0.59) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL6941434 0.77 KDM4E (0.54) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL5511434 0.77 KDM4E (0.53) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL209445 0.76 ALDH1A1 (0.55) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL6943981 0.76 KDM4E (0.49) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL4643007 0.74 KDM4E (0.58) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL282647 0.73 KDM4E (0.58) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL3146899 0.73 KDM4E (0.53) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL31336377 0.73 KDM4E (0.58) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL29374906 0.73 KDM4E (0.53) ALDH1A1KMT2APTK2BKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed