Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209445 | 0.84 | ALDH1A1 (0.55) | KDM4EKMT2AMEN1RECQLHTT | |
| SCHEMBL4600481 | 0.84 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHTT | |
| SCHEMBL28598129 | 0.83 | KDM4E (0.54) | KDM4EKMT2AMEN1RECQLHTT | |
| SCHEMBL5508342 | 0.80 | PPARA (0.46) | TSHRCYP3A4TP53MAPK1PPARG | |
| SCHEMBL212426 | 0.79 | ALDH1A1 (0.59) | KDM4EKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL28049678 | 0.79 | PPARG (0.48) | ALDH1A1TSHRLMNAPPARGPPARA | |
| SCHEMBL4756797 | 0.79 | PPARG (0.48) | ALDH1A1TSHRLMNAPPARGPPARA | |
| SCHEMBL6943981 | 0.79 | KDM4E (0.49) | KDM4EKMT2AMEN1RECQLHTT | |
| Hydrochloric Acid SCHEMBL28541924 | 0.79 | KDM4E (0.49) | KDM4EKMT2AMEN1RECQLHTT | |
| SCHEMBL28220415 | 0.77 | LMNA (0.69) | KDM4EKMT2AMEN1RECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246627-A4 | POLYANHYDRIDES WITH BIOLOGICALLY ACTIVE DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1246627-A2 | POLYANHYDRIDES WITH BIOLOGICALLY ACTIVE DEGRADATION PRODUCTS | Rutgers, The State University of New Jersey (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1032605-A4 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001028492-A2 | POLYANHYDRIDES WITH BIOLOGICALLY ACTIVE DEGRADATION PRODUCTS | RUTGERS, THE STATE UNIVERSITY (US) | 2001-04-26 | — | — | WO | disclosed |
| EP-1032605-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | Rutgers, The State University (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999012990-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | RUTGERS, THE STATE UNIVERSITY (US) | 1999-03-18 | — | — | WO | disclosed |