Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209445 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL5517653 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL30211332 | 0.80 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL2049483 | 0.80 | ALDH1A1 (0.89) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL5520993 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL4420937 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL6941434 | 0.79 | KDM4E (0.54) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL212173 | 0.78 | ALDH1A1 (0.79) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL5516789 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KMT2APTK2BKDM4EHTT | |
| SCHEMBL25788261 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2APTK2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088405-B2 | Therapeutic compositions and methods | Rutgers, The State University of New Jersery (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110223232-A1 | DRUG-RELEASE COMPOSITION HAVING A THERAPEUTIC CARRIER | SILICON VALLEY BANK | 2011-09-15 | — | — | US | disclosed |
| US-8017714-B2 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100074937-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2010-03-25 | — | — | US | disclosed |
| EP-1261347-B1 | THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING PERIODONTITIS WITH ANTIINFLAMATORY COMPOUNDS | UNIV RUTGERS (US) | 2009-09-30 | — | — | EP | disclosed |
| EP-2095817-A1 | Therapeutic compositions and methods | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-1032605-B1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070014832-A1 | Therapeutic compositions and methods | RUTGERS, THE STATE UNIVESITY OF NEW JERSEY | 2007-01-18 | — | — | US | disclosed |
| US-7122615-B1 | Polyanhydrides with therapeutically useful degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1246627-B1 | POLYANHYDRIDES WITH BIOLOGICALLY ACTIVE DEGRADATION PRODUCTS | UNIV RUTGERS (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1464673-A2 | Polyanhydrides with biologically active degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20040038948-A1 | Therapeutic compositions and methods | UHRICH KATHRYN E (US) | 2004-02-26 | — | — | US | disclosed |
| US-6685928-B2 | ADMINISTERING AN EFFECTIVE AMOUNT OF AN ANTI-INFLAMMATORY AGENT TO OR NEAR THE TISSUE TO PROMOTE HEALING OF TISSUE; USEFUL IN DENTAL AND ORTHOPEDIC APPLICATIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2004-02-03 | — | — | US | disclosed |
| US-20030035787-A1 | Polyanhydrides with biologically active degradation products | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2003-02-20 | — | — | US | disclosed |
| US-6468519-B1 | DEPOLYMERIZATION OF BIOCOMPATIBLE TREATMENT AGENT PROVIDING ALPHAHYDROXYACIDS SUCH AS CITRIC ACID OR MALIC ACID; CREAMS, MOISTURIZERS, CLEANSERS, LOTIONS, SHAMPOOS, LIPSTICKS; SMOOTHER, CLEARER SKIN WITH FEWER WRINKLES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2002-10-22 | — | — | US | disclosed |
| US-20020106345-A1 | Therapeutic compositions and methods | POLYMERIX CORPORATION | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020106345-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | ALDH1A1 2968/4885KMT2A 4312/4885PTK2B 1315/4885 |
| US-20110223232-A1 | DRUG-RELEASE COMPOSITION HAVING A THERAPEUTIC CARRIER | ABCB1, ABCB11, ABCC1 | ALDH1A1 3485/4885KMT2A 4675/4885PTK2B 3360/4885 |
| US-20070014832-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | ALDH1A1 2968/4885KMT2A 4312/4885PTK2B 1315/4885 |
| US-20040038948-A1 | Therapeutic compositions and methods | COL2A1, BMP2, BMP4 | ALDH1A1 2968/4885KMT2A 4312/4885PTK2B 1315/4885 |
| US-20100074937-A1 | POLYANHYDRIDES WITH THERAPEUTICALLY USEFUL DEGRADATION PRODUCTS | AADAT, PAH, APEH | ALDH1A1 602/4885KMT2A 2177/4885PTK2B 1093/4885 |
| US-20030035787-A1 | Polyanhydrides with biologically active degradation products | SI, HAAO, GUSB | ALDH1A1 269/4885KMT2A 4302/4885PTK2B 3552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.