Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530656 | 1.00 | MEN1 (0.40) | MEN1KMT2ACTSBALDH1A1HPGD | |
| SCHEMBL5524246 | 1.00 | MEN1 (0.40) | MEN1KMT2ACTSBALDH1A1HPGD | |
| SCHEMBL7125507 | 0.94 | GAA (0.41) | MEN1KMT2ACTSBALDH1A1HPGD | |
| SCHEMBL5955033 | 0.92 | FKBP1A (0.39) | MEN1KMT2ACTSBALDH1A1HPGD | |
| SCHEMBL5954914 | 0.89 | KMT2A (0.45) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL5955901 | 0.85 | KMT2A (0.42) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL5955729 | 0.85 | KMT2A (0.41) | MEN1KMT2ACTSBALDH1A1HPGD | |
| Benzene SCHEMBL5530659 | 0.84 | CTSS (0.43) | CTSBPOLBSMN1; SMN2CTSSCTSL | |
| Benzene SCHEMBL5524247 | 0.84 | CTSS (0.43) | CTSBPOLBSMN1; SMN2CTSSCTSL | |
| Benzene SCHEMBL5522213 | 0.84 | CTSS (0.43) | CTSBPOLBSMN1; SMN2CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232654-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232654-A1 | Novel Compounds and Compositions as Cathepsin Inhibitors | CTSS, CTSB, CTSE | MEN1 4485/4885KMT2A 4623/4885CTSB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.