Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527609 | 0.88 | CACNA1G (0.38) | SMN1; SMN2ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL5526019 | 0.87 | TRPM8 (0.45) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5520170 | 0.87 | KMT2A (0.46) | SMN1; SMN2KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL5524844 | 0.87 | CHRM4 (0.39) | SMN1; SMN2ALDH1A1DHFRACMSD | |
| SCHEMBL5527759 | 0.86 | DHFR (0.48) | SMN1; SMN2ALDH1A1KDM4EDHFRBCL2 | |
| SCHEMBL5521998 | 0.84 | HCAR2 (0.46) | SMN1; SMN2ALDH1A1RAB9ANPC1GPR52 | |
| SCHEMBL5556229 | 0.84 | DHFR (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5528442 | 0.81 | NR1H4 (0.43) | SMN1; SMN2RAB9ADHFR | |
| SCHEMBL5522256 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL5528655 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | SMN1; SMN2 4646/4885ALDH1A1 2042/4885MEN1 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.