Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535331 | 0.91 | LMNA (0.46) | IGF1RDHFRLRRK2RAB9ASMN1; SMN2 | |
| SCHEMBL5529329 | 0.88 | HTT (0.45) | AURKAPTK2LRRK2NPC1RAB9A | |
| SCHEMBL5528704 | 0.88 | TNK2 (0.36) | DHFRHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4199140 | 0.87 | KDM4E (0.41) | IGF1RTSHRDHFRLRRK2NPC1 | |
| SCHEMBL5525215 | 0.87 | DHFR (0.39) | IGF1RTSHRDHFRPTK2HDAC3 | |
| SCHEMBL5523567 | 0.87 | MAPT (0.38) | AURKAPTK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2115650 | 0.84 | IGF1R (0.46) | IGF1RULK1TSHRDHFRAURKA | |
| SCHEMBL5525987 | 0.83 | NPC1 (0.41) | DHFRAURKALRRK2NPC1RAB9A | |
| SCHEMBL5530876 | 0.83 | CNR2 (0.34) | ULK1DHFRNPC1RAB9A | |
| SCHEMBL2113595 | 0.82 | IGF1R (0.44) | IGF1RULK1TSHRDHFRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293525-A1 | 2-ANILINO-4-AMINOALKYLENEAMINOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-12-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293525-A1 | 2-ANILINO-4-AMINOALKYLENEAMINOPYRIMIDINES | PRKCA, PRKCH, PRKCG | IGF1R 4009/4885ULK1 1521/4885TSHR 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.