Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 10/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22558694 | 0.87 | DGAT1 (0.43) | DGAT1ALDH1A1KDM4ECPB2OPRM1 | |
| SCHEMBL15897081 | 0.84 | RAB9A (0.42) | DGAT1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL27639608 | 0.80 | DGAT1 (0.38) | DGAT1ALDH1A1KDM4ECPB2OPRM1 | |
| SCHEMBL22290800 | 0.79 | DGAT1 (0.38) | DGAT1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28757857 | 0.79 | DGAT1 (0.45) | DGAT1ALDH1A1KDM4ECPB2OPRM1 | |
| SCHEMBL20919672 | 0.78 | RAB9A (0.40) | DGAT1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL349475 | 0.77 | RORC (0.41) | DGAT1ALDH1A1OPRM1RAB9ANPC1 | |
| SCHEMBL5519762 | 0.77 | DGAT1 (0.41) | DGAT1ALDH1A1KDM4ECPB2RAB9A | |
| SCHEMBL5526276 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EOPRM1OPRL1RAB9A | |
| SCHEMBL22615353 | 0.76 | DGAT1 (0.40) | DGAT1ALDH1A1KDM4ECPB2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185132-A1 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereo | MERCK & CO., INC. | 2007-08-09 | — | — | US | disclosed |
| CN-1816545-A | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof | MERCK & CO INC (US) | 2006-08-09 | — | — | CN | disclosed |
| EP-1654259-A1 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005005420-A1 | CYCLOPROPYL GROUP SUBSTITUTED OYAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185132-A1 | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereo | IL17A, COASY, OXA1L | DGAT1 2690/4885ALDH1A1 1166/4885KDM4E 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.