SCHEMBL5524545

SCHEMBL5524545

O=C(O)CCCCNc1cccnc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
MAPT P10636 2/20 0.46
CYP1A2 P05177 2/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 7/20 0.45
HSD17B10 Q99714 2/20 0.45
HPGD P15428 1/20 0.45
ASPH Q12797 2/20 0.44
KDM8 Q8N371 2/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
BLM P54132 1/20 0.44
AGER Q15109 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SHMT2 P34897 1/20 0.43
ITGB3 P05106 1/20 0.43
ITGAV P06756 1/20 0.43
NR4A2 P43354 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515567 0.95 KDM4E (0.47) KDM4EMAPTCYP1A2HTTALDH1A1
SCHEMBL14882255 0.84 PTPN1 (0.51) KDM4EMAPTCYP1A2HTTALDH1A1
SCHEMBL13978034 0.80 KDM4E (0.53) KDM4EMAPTCYP1A2ALDH1A1ASPH
SCHEMBL6670720 0.76 ALDH1A1 (0.54) KDM4ECYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL5510920 0.75 ALDH1A1 (0.78) KDM4EMAPTALDH1A1HSD17B10HPGD
SCHEMBL2037116 0.74 ITGB3 (0.70) ITGB3ITGAV
SCHEMBL5518973 0.74 ALDH1A1 (0.76) KDM4EMAPTALDH1A1HSD17B10HPGD
SCHEMBL5514066 0.74 ALDH1A1 (0.76) KDM4EMAPTALDH1A1HSD17B10HPGD
SCHEMBL25466063 0.73 KDM4E (0.41) KDM4EMAPTCYP1A2HTTALDH1A1
SCHEMBL8487866 0.73 KDM4E (0.46) KDM4EMAPTCYP1A2HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed