Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815564 | 0.91 | PPARD (0.64) | PPARDFFAR1PPARGPPARACYP2C9 | |
| SCHEMBL14378490 | 0.79 | FFAR1 (0.64) | PPARDFFAR1PPARGPPARACYP2C9 | |
| SCHEMBL14378597 | 0.79 | PPARA (0.71) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL14402406 | 0.79 | PPARD (0.60) | PPARDFFAR1PPARGPPARACYP2C9 | |
| SCHEMBL14378585 | 0.78 | PPARD (0.69) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL14378593 | 0.78 | PPARD (0.69) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL14378606 | 0.78 | PPARD (0.64) | PPARDFFAR1PPARGPPARA | |
| SCHEMBL14412915 | 0.77 | PPARD (0.59) | PPARDFFAR1PPARGPPARACYP2C9 | |
| SCHEMBL14378611 | 0.76 | FFAR1 (0.66) | PPARDFFAR1PPARGPPARACYP2C9 | |
| SCHEMBL14378618 | 0.74 | PPARD (0.55) | PPARDFFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244155-A1 | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders | AMGEN INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244155-A1 | Bicyclic carboxylic acid derivatives useful for treating metabolic disorders | GOT2, PC, GOT1 | PPARD 243/4885FFAR1 326/4885PPARG 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.