Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LHCGR | P22888 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528446 | 0.85 | RXRA (0.50) | SMN1; SMN2LMNAKMOALDH1A1 | |
| SCHEMBL5525381 | 0.84 | CDC7 (0.54) | SMN1; SMN2LMNAPTGDR2ALDH1A1PTGS2 | |
| SCHEMBL5522187 | 0.84 | TRPV1 (0.48) | TRPV1TRPM8SMN1; SMN2KMOPIN1 | |
| SCHEMBL5522085 | 0.83 | PTGS2 (0.56) | SMN1; SMN2PTGDR2ALDH1A1PTGS2 | |
| SCHEMBL1338860 | 0.82 | TRPM8 (0.49) | TRPM8SMN1; SMN2LMNAPTGDR2KMO | |
| SCHEMBL5528299 | 0.82 | CDC7 (0.51) | SMN1; SMN2LMNAPTGDR2ALDH1A1PTGS2 | |
| SCHEMBL14705596 | 0.81 | PTGDR2 (0.48) | TRPM8SMN1; SMN2LMNAPTGDR2KMO | |
| SCHEMBL5524362 | 0.80 | CA12 (0.44) | SMN1; SMN2 | |
| SCHEMBL5520109 | 0.80 | KMO (0.44) | TRPV1SMN1; SMN2KMOPTGS2 | |
| SCHEMBL5556214 | 0.79 | TRPM8 (0.49) | TRPM8SMN1; SMN2LMNAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | TRPV1 4123/4885TRPM8 3522/4885SMN1; SMN2 4646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.