Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 4/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517694 | 0.90 | MARS1 (0.57) | MARS1SLC16A3KDRALDH1A1KDM4E | |
| SCHEMBL5524892 | 0.87 | CNR1 (0.48) | MARS1FYNSLC16A3KDRJAK1 | |
| SCHEMBL4933639 | 0.82 | FYN (0.48) | MARS1FYNSLC16A3JAK1SMN1; SMN2 | |
| SCHEMBL3864148 | 0.81 | MARS1 (0.49) | MARS1SLC16A3SMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL5270243 | 0.78 | SMN1; SMN2 (0.40) | FYNJAK1SMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL5266512 | 0.77 | KDM4E (0.42) | MARS1FYNSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL2914740 | 0.77 | GRM5 (0.40) | SLC16A3ALDH1A1GAATSHRKDM4E | |
| SCHEMBL28110540 | 0.76 | POLB (0.47) | ALDH1A1POLBGAATSHRKDM4E | |
| SCHEMBL6454155 | 0.75 | ALDH1A1 (0.53) | MARS1SLC16A3ALDH1A1POLBGAA | |
| SCHEMBL3864153 | 0.74 | ALDH1A1 (0.40) | MARS1SLC16A3SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MARS1 2982/4885FYN 1714/4885SLC16A3 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.