Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528701 | 1.00 | MEN1 (0.40) | MEN1KMT2AL3MBTL1LMNANPSR1 | |
| SCHEMBL5622851 | 1.00 | MEN1 (0.40) | MEN1KMT2AL3MBTL1LMNANPSR1 | |
| P-Toluenesulfonamide SCHEMBL5525016 | 0.82 | CA2 (0.49) | KIF11AKR1B1 | |
| P-Toluenesulfonamide SCHEMBL5523959 | 0.82 | CA2 (0.49) | KIF11AKR1B1 | |
| P-Toluenesulfonamide SCHEMBL5528880 | 0.82 | CA2 (0.49) | KIF11AKR1B1 | |
| SCHEMBL5523601 | 0.81 | MEN1 (0.36) | MEN1KMT2AL3MBTL1LMNANPSR1 | |
| SCHEMBL788818 | 0.77 | KDM1A (0.50) | LMNAKDM1AMAOB | |
| SCHEMBL29529186 | 0.77 | KDM1A (0.50) | LMNAKDM1AMAOB | |
| SCHEMBL2147836 | 0.77 | KDM1A (0.50) | LMNAKDM1AMAOB | |
| SCHEMBL30664080 | 0.77 | KDM1A (0.50) | LMNAKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293682-A1 | Methods of Preparing Sulfinamides and Sulfoxides | APSINTERM, LLC | 2007-12-20 | — | — | US | disclosed |
| US-7256297-B2 | Methods of preparing sulfinamides and sulfoxides | APSINTERM, LLC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-7064214-B2 | Methods of preparing sulfinamides and sulfoxides | APSINTERM LLC (US) | 2006-06-20 | — | — | US | disclosed |
| US-20060128767-A1 | Methods of preparing sulfinamides and sulfoxides | SENANAYAKE CHRIS H | 2006-06-15 | — | — | US | disclosed |
| US-20030083517-A1 | Methods of preparing sulfinamides and sulfoxides | APSINTERM LLC | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128767-A1 | Methods of preparing sulfinamides and sulfoxides | STS, TST, CBS | MEN1 1917/4885KMT2A 1066/4885L3MBTL1 4783/4885 |
| US-20070293682-A1 | Methods of Preparing Sulfinamides and Sulfoxides | STS, TST, CBS | MEN1 1917/4885KMT2A 1066/4885L3MBTL1 4783/4885 |
| US-20030083517-A1 | Methods of preparing sulfinamides and sulfoxides | STS, TST, CBS | MEN1 1917/4885KMT2A 1066/4885L3MBTL1 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.