Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526528 | 1.00 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DBCL2 | |
| SCHEMBL14364442 | 0.91 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DMCL1 | |
| SCHEMBL8221428 | 0.89 | BCL2 (0.38) | BCL2MCL1 | |
| SCHEMBL14364439 | 0.89 | BCL2 (0.38) | BCL2MCL1 | |
| SCHEMBL1014380 | 0.84 | BCL2 (0.44) | BCL2MCL1POLB | |
| SCHEMBL4791746 | 0.84 | BCL2 (0.44) | BCL2MCL1POLB | |
| SCHEMBL14364443 | 0.80 | PTGES (0.37) | MCL1POLB | |
| SCHEMBL5570893 | 0.80 | BCL2L1 (0.43) | MCL1POLB | |
| SCHEMBL1013961 | 0.77 | STS (0.46) | MCL1YAP1 | |
| SCHEMBL1070360 | 0.77 | STS (0.46) | MCL1YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070265281-A1 | Organic Compounds and Their Uses | COTTENS SYLVAIN | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265281-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | PDE4A 3448/4885PDE4B 3578/4885PDE4C 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.