Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10646149 | 0.84 | KDM4E (0.45) | NPSR1HTTALDH1A1KDM4EMAPT | |
| SCHEMBL9047001 | 0.84 | KDM4E (0.45) | NPSR1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL14276601 | 0.80 | SLC9A1 (0.52) | ALDH1A1KDM4EMAPTNPY5RSLC9A1 | |
| SCHEMBL5526688 | 0.80 | NPY5R (0.44) | NPSR1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL5473951 | 0.80 | LMNA (0.53) | NPSR1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL5525205 | 0.78 | NPSR1 (0.44) | NPSR1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL5526920 | 0.76 | NPSR1 (0.43) | NPSR1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL5525304 | 0.76 | NPSR1 (0.43) | NPSR1HTTKMT2ATSHRALDH1A1 | |
| SCHEMBL4844072 | 0.76 | KDM4E (0.49) | NPSR1HTTKMT2AALDH1A1KDM4E | |
| SCHEMBL6390066 | 0.74 | MAPT (0.41) | NPSR1HTTKMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | PEES KLAUS-JUERGEN | 2007-09-06 | — | — | US | disclosed |
| US-7230104-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2005-12-22 | — | — | US | disclosed |
| EP-1577312-A1 | Triazolopyrimidine intermediate compounds for fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-21 | — | — | EP | disclosed |
| US-6943252-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-13 | — | — | US | disclosed |
| EP-1289963-B1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | PEES KLAUS-JUERGEN | 2004-07-29 | — | — | US | disclosed |
| US-6632821-B2 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | BASF AKTIENGESELLSCHAFT | 2003-05-08 | — | — | US | disclosed |
| EP-1289963-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096314-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147744-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, NOX5 | NPSR1 918/4885HTT 4099/4885KMT2A 3639/4885 |
| US-20050282828-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, CBR1, CYP3A5 | NPSR1 1110/4885HTT 4218/4885KMT2A 3583/4885 |
| US-20070208037-A1 | FUNGICIDAL 5-PHENYL SUBSTITUTED 2-(CYANOAMINO) PYRIMIDINES | CBR3, NOX5, CBR1 | NPSR1 440/4885HTT 4154/4885KMT2A 3579/4885 |
| US-20030088096-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR1, CBR3, ARSA | NPSR1 54/4885HTT 4173/4885KMT2A 3683/4885 |
| US-20050282847-A1 | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines | CBR3, NOX5, CBR1 | NPSR1 327/4885HTT 4163/4885KMT2A 3726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.