Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28289368 | 0.98 | MAPT (0.46) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL6489524 | 0.88 | GPR3 (0.50) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| Hydrogen Sulfide SCHEMBL29100291 | 0.86 | GPR3 (0.48) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL16243459 | 0.83 | MAPT (0.50) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL28076011 | 0.83 | GPR3 (0.45) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| Trifluoromethanesulfonic Acid SCHEMBL29631864 | 0.80 | SLC9A1 (0.44) | MAPTHPGDMAOAMAOBMEN1 | |
| SCHEMBL20262961 | 0.77 | MAPT (0.50) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL9128466 | 0.77 | MAPT (0.50) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL28096180 | 0.75 | MAPT (0.49) | MAPTNPC1RAB9AHPGDCYP1A2 | |
| SCHEMBL357103 | 0.75 | MAPT (0.43) | MAPTNPC1RAB9AHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109674754-B | Flupentixol and melitracen pharmaceutical composition and preparation thereof | 广东赛烽医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-109674754-B | Flupentixol and melitracen pharmaceutical composition and preparation thereof | 广东赛烽医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-109771386-B | Flupentixol melitracen tablet and preparation method thereof | 广东赛烽医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-109771386-B | Flupentixol melitracen tablet and preparation method thereof | 广东赛烽医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| US-10838302-B2 | Cross-linkable fluorinated photopolymer | ORTHOGONAL, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-20200301276-A1 | CROSS-LINKABLE FLUORINATED PHOTOPOLYMER | ORTHOGONAL, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-10739680-B2 | Cross-linkable fluorinated photopolymer | ORTHOGONAL, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| WO-2020143394-A1 | FLUPENTIXOL/MELITRACEN PHARMACEUTICAL COMPOSITION AND PREPARATION THEREOF | 广东赛烽医药科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| WO-2020143395-A1 | FLUPENTIXOL MELITRACEN TABLET AND PREPARATION METHOD THEREFOR | 广东赛烽医药科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| WO-2020143395-A1 | FLUPENTIXOL MELITRACEN TABLET AND PREPARATION METHOD THEREFOR | 广东赛烽医药科技有限公司 | 2020-07-16 | — | — | WO | disclosed |
| CN-109771386-A | A kind of Flupentixol and Melitracen Tablets agent and preparation method thereof | 广东赛烽医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |
| US-10289000-B2 | Cross-linkable fluorinated photopolymer | ORTHOGONAL, INC. (US) | 2019-05-14 | — | — | US | disclosed |
| CN-109674754-A | A kind of flupentixol and melitracen pharmaceutical composition and its preparation | 广东赛烽医药科技有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109674754-A | A kind of flupentixol and melitracen pharmaceutical composition and its preparation | 广东赛烽医药科技有限公司 | 2019-04-26 | — | — | CN | disclosed |
| US-20180275517-A1 | CROSS-LINKABLE FLUORINATED PHOTOPOLYMER | ORTHOGONAL INC (US) | 2018-09-27 | — | — | US | disclosed |
| US-9958778-B2 | Cross-linkable fluorinated photopolymer | ORTHOGONAL, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160349614-A1 | CROSS-LINKABLE FLUORINATED PHOTOPOLYMER | ORTHOGONAL, INC. | 2016-12-01 | — | — | US | disclosed |
| CN-103450151-B | Preparing method of flupentixol compound | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-103450151-A | Flupentixol compound | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2013-12-18 | — | — | CN | disclosed |
| WO-2007022077-A2 | HOOF REPAIR MATERIAL | JOHNSTON ALLEN D (US) | 2007-02-22 | — | — | WO | disclosed |