Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 6/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.76 |
| ▸ | HTR1A | P08908 | 8/20 | 0.64 |
| ▸ | HTR1D | P28221 | 8/20 | 0.64 |
| ▸ | HTR1B | P28222 | 8/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 5/20 | 0.58 |
| ▸ | HTR7 | P34969 | 5/20 | 0.58 |
| ▸ | DRD3 | P35462 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | HTR6 | P50406 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229816 | 0.84 | NCF1 (0.76) | NCF1CYP2C9ADRB2ADRB1USP2 | |
| SCHEMBL13438227 | 0.84 | HRH3 (0.59) | NCF1CYP2C9KCNH2 | |
| SCHEMBL6125246 | 0.82 | NCF1 (0.75) | NCF1ADRB2ADRB1USP2LMNA | |
| SCHEMBL13438233 | 0.82 | NCF1 (0.56) | NCF1CYP2C9HTR1AHTR1DHTR1B | |
| SCHEMBL13438228 | 0.82 | NCF1 (0.56) | NCF1CYP2C9HTR1AHTR1DHTR1B | |
| SCHEMBL5065450 | 0.81 | NCF1 (0.88) | NCF1ADRB2ADRB1USP2LMNA | |
| SCHEMBL30511704 | 0.79 | NCF1 (0.97) | NCF1ADRB2ADRB1USP2LMNA | |
| SCHEMBL2878229 | 0.78 | HTR1A (1.00) | CYP2C9HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL2880901 | 0.78 | CYP2C9 (0.79) | CYP2C9HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL2884757 | 0.78 | CYP2C9 (0.79) | CYP2C9HTR1AHTR1DHTR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | NCF1 2805/4885CYP2C9 4543/4885HTR1A 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.