Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 12/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519910 | 0.85 | RBP4 (0.43) | GBA1SMN1; SMN2HSD17B10LMNANPC1 | |
| SCHEMBL5524235 | 0.84 | ALDH1A1 (0.45) | GBA1SMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL10266309 | 0.77 | GBA1 (0.44) | GBA1HSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL17916135 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HSD17B10LMNANPC1RAB9A | |
| SCHEMBL1420176 | 0.74 | RBP4 (0.42) | HSD17B10HPGD | |
| SCHEMBL5528147 | 0.73 | PIK3CA (0.47) | HSD17B10LMNAALDH1A1 | |
| SCHEMBL12548172 | 0.72 | GBA1 (0.46) | GBA1SMN1; SMN2HSD17B10LMNAHPGD | |
| SCHEMBL5525363 | 0.71 | HRH4 (0.46) | HSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL5527465 | 0.71 | KDM4E (0.58) | HSD17B10HPGDALDH1A1TSHRMEN1 | |
| SCHEMBL12549092 | 0.71 | HRH4 (0.42) | SMN1; SMN2HSD17B10LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | GBA1 1662/4885SMN1; SMN2 4646/4885HSD17B10 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.