SCHEMBL5528151

SCHEMBL5528151

O=C(Cc1cc(Br)cc(Br)c1)Cc1cc(Br)cc(Br)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.39
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ACP1 P24666 1/20 0.35
EPHX1 P07099 1/20 0.35
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
GSK3B P49841 1/20 0.34
THRB P10828 1/20 0.34
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
RAB9A P51151 1/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2281695 0.82 THRB (0.50) LMNAALDH1A1THRBGAAMAPT
SCHEMBL5391144 0.80 CA2 (0.46) IDO1EPHX1ALDH1A1
Potassium Ion SCHEMBL4185278 0.80 GPR84 (0.44) IDO1ACP1EPHX1THRBEGFR
SCHEMBL4187668 0.80 IDO1 (0.37) IDO1ACP1EPHX1LMNAALDH1A1
Hydrochloric Acid SCHEMBL5409279 0.78 CA2 (0.45) IDO1EPHX1ALDH1A1
SCHEMBL2164880 0.78 F2 (0.42) IDO1CES2CES1EPHX1ALDH1A1
SCHEMBL24197592 0.77 THRB (0.50) LMNAALDH1A1THRBGAAMAPT
SCHEMBL1448505 0.77 EGFR (0.53) IDO1NPC1EGFRERBB2
SCHEMBL4201900 0.75 THRB (0.36) IDO1LMNAALDH1A1GSK3BTHRB
SCHEMBL6047068 0.75 THRB (0.33) IDO1ACP1EPHX1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096300-A1 NOVEL METHODS FOR THE PREPARATION OF 3-AZABICYLCO[3.1,0]HEXANE-6-CARBOXAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2025-05-08 WO disclosed
US-20070027280-A1 Multifunctional substituted monomers and polyarylene compositions therefrom HAHNFELD JERRY L 2007-02-01 US disclosed
WO-2004090018-A1 MULTIFUNCTIONAL SUBSTITUTED MONOMERS AND POLYARYLENE COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2004-10-21 WO disclosed