Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.36 |
| ▸ | THRA | P10827 | 5/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187668 | 0.95 | IDO1 (0.37) | THRBTHRAGSK3BIDO1GPR35 | |
| SCHEMBL5194940 | 0.87 | GPR84 (0.37) | THRBTHRAGSK3BGPR84MAPT | |
| SCHEMBL22594983 | 0.81 | LMNA (0.37) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL77287 | 0.79 | EGFR (0.50) | THRBTHRAIDO1EGFRERBB2 | |
| SCHEMBL24197592 | 0.78 | THRB (0.50) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL12704178 | 0.78 | TPMT (0.42) | IDO1RAB9A | |
| SCHEMBL1149702 | 0.76 | MEN1 (0.50) | EGFRERBB2MEN1KMT2AMAPT | |
| SCHEMBL5528151 | 0.75 | IDO1 (0.39) | THRBGSK3BIDO1EGFRERBB2 | |
| SCHEMBL2281695 | 0.73 | THRB (0.50) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL23276556 | 0.73 | HSP90AB1 (0.54) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476416-B1 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| US-7635741-B2 | Curable polyacetylenes used as dielectrics in making microelectronics such as integrated circuits | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-22 | — | — | US | disclosed |
| EP-1476416-A2 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20040053033-A1 | Multifunctional monomers and their use in making cross-linked polymers and porous films | NIU Q JASON (US) | 2004-03-18 | — | — | US | disclosed |
| WO-2003068825-A2 | MULTIFUNCTIONAL MONOMERS AND THEIR USE IN MAKING CROSS-LINKED POLYMERS AND POROUS FILMS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-08-21 | — | — | WO | disclosed |