1-Naphthol

1-Naphthol

SCHEMBL7997314

Cc1ccc(O)cc1.Oc1cccc2ccccc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.68
ACHE P22303 1/20 0.52
HSD17B1 P14061 2/20 0.52
HSD17B2 P37059 2/20 0.52
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
CYP2C19 P33261 1/20 0.51
NQO2 P16083 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP2A6 P11509 1/20 0.45
KMT2A Q03164 4/20 0.45
RAB9A P51151 3/20 0.45
MEN1 O00255 3/20 0.45
NPC1 O15118 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HKDC1 Q2TB90 1/20 0.44
RRM1 P23921 1/20 0.44
KDM4A O75164 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
KDM4C Q9H3R0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL6742778 0.90 CYP1A2 (0.69) CYP1A2ACHEHSD17B1HSD17B2ESR1
1-Naphthol SCHEMBL94756 0.83 CYP1A2 (0.81) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL28448239 0.83 CYP1A2 (0.81) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL29959385 0.83 CYP1A2 (0.81) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL10627914 0.83 CYP1A2 (0.90) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL10486461 0.82 CYP1A2 (1.00) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL273260 0.82 CYP1A2 (1.00) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL3416 0.82 CYP1A2 (1.00) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL29767730 0.82 CYP1A2 (1.00) CYP1A2HSD17B1HSD17B2ESR1ESR2
1-Naphthol SCHEMBL3836716 0.81 CYP1A2 (0.77) CYP1A2ACHEHSD17B1HSD17B2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297332-B1 FOR SEALING A SEMICONDUCTOR INTEGRATED CIRCUIT, AMINOPHOSPHINE OXIDE AS IMPROVED ACCELERATING AGENT, PACKAGE BETTER IN CRACK RESISTANCE MITSUI CHEMICALS, INC. (JP) 2001-10-02 US disclosed
EP-0953588-A2 An epoxy-resin composition and use thereof Mitsui Chemicals, Inc. (JP) 1999-11-03 EP disclosed