Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532781 | 0.89 | NPC1 (0.42) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL5535174 | 0.85 | MAPT (0.46) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL5535769 | 0.82 | GABRP (0.42) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL5528306 | 0.82 | KMT2A (0.47) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL5530790 | 0.81 | NPC1 (0.43) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5532784 | 0.78 | PDE4A (0.52) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL5531131 | 0.77 | RAB9A (0.47) | MEN1KMT2AALDH1A1HTTRAB9A | |
| SCHEMBL5538626 | 0.77 | MAPT (0.57) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL4029345 | 0.75 | POLB (0.45) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL5533387 | 0.74 | NPC1 (0.47) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |