SCHEMBL5530140

SCHEMBL5530140

O=c1c2c(C(F)(F)F)c3c(=O)n(Cc4ccccc4)c(=O)c3c(C(F)(F)F)c2c(=O)n1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 4/20 0.47
GSK3B P49841 4/20 0.47
CFTR P13569 1/20 0.44
P2RX4 Q99571 1/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
F2 P00734 1/20 0.42
PLG P00747 1/20 0.42
ELANE P08246 1/20 0.42
CTSG P08311 1/20 0.42
CMA1 P23946 1/20 0.42
CTRC Q99895 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12895972 0.81 SRC (0.50) GSK3AGSK3BCFTRP2RX4ALDH1A1
SCHEMBL8985073 0.71 GSK3B (0.67) GSK3AGSK3BP2RX4ALDH1A1KDM4E
SCHEMBL22203802 0.71 SRC (0.62) GSK3AGSK3BP2RX4ALDH1A1KDM4E
SCHEMBL14392803 0.71 ALDH1A1 (0.67) GSK3AGSK3BP2RX4ALDH1A1KDM4E
SCHEMBL12179986 0.70 P2RX3 (0.49) CFTRALDH1A1KDM4ESMN1; SMN2RGS4
SCHEMBL12179838 0.70 P2RX3 (0.52) CFTRALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL1729534 0.69 GSK3B (0.59) GSK3AGSK3BP2RX4ALDH1A1KDM4E
SCHEMBL9061909 0.69 L3MBTL1 (0.52) GSK3AGSK3BMEN1KMT2AHPGD
SCHEMBL12179822 0.69 P2RX3 (0.48) CFTRALDH1A1KDM4ESMN1; SMN2SRC
SCHEMBL16652312 0.68 POLB (0.47) GSK3AGSK3BCFTRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed