Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744801 | 0.83 | MMP2 (0.49) | ALDH1A1KDM4ESMN1; SMN2G6PDCASP7 | |
| SCHEMBL725315 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL29876454 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL1919550 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL15060465 | 0.77 | G6PD (0.69) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL29386467 | 0.77 | G6PD (0.69) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL135374 | 0.77 | PLK1 (0.45) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL28429427 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL8081427 | 0.77 | HNF4A (0.69) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL8747590 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638575-A | Method for preparing key intermediate of eltrombopag by one-pot method | 浙江国邦药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116874428-B | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-116874428-A | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2023-10-13 | — | — | CN | disclosed |
| EP-1805155-A1 | THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047344-A1 | THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | disclosed |