Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 14/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969517 | 0.80 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CALDH1A1MAPKAPK2 | |
| SCHEMBL2969080 | 0.75 | SMN1; SMN2 (0.51) | ADRA2AADRA2BADRA2CALDH1A1USP2 | |
| SCHEMBL7356180 | 0.71 | KMT2A (0.70) | ADRA2AADRA2BADRA2CALDH1A1USP2 | |
| SCHEMBL9764697 | 0.63 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL29441579 | 0.62 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPKAPK2 | |
| SCHEMBL739300 | 0.62 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPKAPK2 | |
| SCHEMBL8305870 | 0.62 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPKAPK2 | |
| SCHEMBL4683462 | 0.62 | KCNQ3 (0.45) | KCNJ11 | |
| SCHEMBL28527558 | 0.62 | ALDH1A1 (0.57) | ALDH1A1USP2KMT2AKIF11 | |
| SCHEMBL22115413 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819685-A1 | SUBSTITUTED OXYGUANIDINES | Bayer CropScience AG (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056333-A1 | SUBSTITUTED OXYGUANIDINES | BAYER CROPSCIENCE AG (DE) | 2006-06-01 | — | — | WO | disclosed |