Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.59 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761794 | 0.76 | ALDH1A1 (0.52) | IDO1ALDH1A1 | |
| SCHEMBL9761787 | 0.76 | ALDH1A1 (0.52) | IDO1ALDH1A1 | |
| SCHEMBL7461149 | 0.72 | HTR3E (0.50) | SMN1; SMN2 | |
| SCHEMBL1274032 | 0.71 | — | — | |
| SCHEMBL7668610 | 0.68 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CALDH1A1DGAT1 | |
| SCHEMBL7668616 | 0.68 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CALDH1A1DGAT1 | |
| SCHEMBL9342646 | 0.68 | ITGB3 (0.53) | IDO1TDO2 | |
| SCHEMBL9342643 | 0.68 | ITGB3 (0.53) | IDO1TDO2 | |
| SCHEMBL22115413 | 0.67 | — | — | |
| SCHEMBL11955561 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |