Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835204 | 0.65 | CYP2C9 (0.47) | MAPTGAAALDH1A1HSD17B10MEN1 | |
| SCHEMBL19817425 | 0.65 | BCHE (0.49) | MAPTHPGDGAAALDH1A1HSD17B10 | |
| SCHEMBL6503703 | 0.64 | HTT (0.53) | MAPTHPGDTSHRRECQLLMNA | |
| SCHEMBL1553234 | 0.63 | CYP2C9 (0.45) | MAPTGAAALDH1A1HSD17B10MEN1 | |
| SCHEMBL3181930 | 0.63 | ALDH1A1 (0.32) | MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6495535 | 0.62 | HTT (0.51) | MAPTHPGDTSHRRECQLLMNA | |
| SCHEMBL21163363 | 0.59 | HTT (0.58) | MAPTHPGDTSHRRECQLLMNA | |
| SCHEMBL29944169 | 0.59 | MEN1 (0.72) | HPGDTSHRLMNAALDH1A1MEN1 | |
| SCHEMBL2951307 | 0.59 | MEN1 (0.72) | HPGDTSHRLMNAALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10759949 | 0.58 | MEN1 (0.70) | HPGDTSHRLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871774-B1 | DETECTION OF NUCLEIC ACIDS AND NUCLEIC ACID UNITS | UNIV STRATHCLYDE (GB) | 2007-05-02 | — | — | EP | disclosed |
| US-7045592-B2 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | DEVELOGEN ISRAEL LTD. (IL) | 2006-05-16 | — | — | US | disclosed |
| EP-1097164-A4 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD (IL) | 2005-05-25 | — | — | EP | disclosed |
| US-6664305-B2 | Chromatography material and a process of manufacturing that material | BIA SEPARATIONS D.O.O. (SI) | 2003-12-16 | — | — | US | disclosed |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PEPTOR LTD. (IL) | 2003-10-16 | — | — | US | disclosed |
| US-20030125204-A1 | Chromatography material and a process of manufacturing that material | BIA SEPARATIONS D.O.O. (SI) | 2003-07-03 | — | — | US | disclosed |
| EP-1294480-A1 | A CHROMATOGRAPHY MATERIAL AND A PROCESS OF MANUFACTURING THAT MATERIAL | Bia Separations D.O.O. (SI) | 2003-03-26 | — | — | EP | disclosed |
| US-6512092-B2 | Solid phase peptide synthesis; in situ generation of amino acid chloride by deblocking; coupling sterically hindered amino acid residues | PEPTOR LTD. (IL) | 2003-01-28 | — | — | US | disclosed |
| WO-2002000337-A1 | A CHROMATOGRAPHY MATERIAL AND A PROCESS OF MANUFACTURING THAT MATERIAL | BIA SEPARATIONS D.O.O. (SI) | 2002-01-03 | — | — | WO | disclosed |
| US-20010018503-A1 | Fluorescent water-soluble polymers | NALCO CHEMICAL COMPANY | 2001-08-30 | — | — | US | disclosed |
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | FALB ELIEZER (IL) | 2001-07-05 | — | — | US | disclosed |
| EP-1097164-A1 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD (IL) | 2001-05-09 | — | — | EP | disclosed |
| WO-2001007430-A1 | FLUORESCENT WATER-SOLUBLE POLYMERS | NALCO CHEMICAL COMPANT (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000002898-A1 | PROCESSES FOR COUPLING AMINO ACIDS USING BIS-(TRICHLOROMETHYL) CARBONATE | PEPTOR LTD. (IL) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007037-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | MAPT 3571/4885HPGD 4034/4885TSHR 453/4885 |
| US-20030195331-A1 | Processes for coupling amino acids using bis-(trichloromethyl) carbonate | PTMS, BCAT1, DAO | MAPT 3571/4885HPGD 4034/4885TSHR 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.