Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281349 | 0.82 | IDO1 (0.56) | CA3CA6CA5ACA14CA5B | |
| SCHEMBL29507259 | 0.82 | IDO1 (0.56) | CA3CA6CA5ACA14CA5B | |
| SCHEMBL12804347 | 0.80 | CA3 (0.56) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL27656034 | 0.77 | HSD17B1 (0.53) | KDM4EMPIL3MBTL1HSD17B1HSD17B2 | |
| SCHEMBL484933 | 0.76 | IDO1 (0.68) | KDM4EMPIL3MBTL1IDO1TSHR | |
| SCHEMBL31540836 | 0.76 | IDO1 (0.68) | KDM4EMPIL3MBTL1IDO1TSHR | |
| SCHEMBL29388776 | 0.76 | IDO1 (0.68) | KDM4EMPIL3MBTL1IDO1TSHR | |
| SCHEMBL16494696 | 0.73 | KDM4E (0.53) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL7555229 | 0.70 | MAPT (0.39) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL7555113 | 0.70 | MAPT (0.39) | CA3CA6CA5ACA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161808-A1 | Process for the preparation of aq4n | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-07-12 | — | — | US | disclosed |
| EP-1732881-A2 | PROCESS FOR THE PREPARATION OF AQ4N | Kudos Pharmaceuticals Limited (GB) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005080314-A2 | PROCESS FOR THE PREPARATION OF AQ4N | KUDOS PHARMACEUTICALS LIMITED (GB) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161808-A1 | Process for the preparation of aq4n | AQP1, AQP4, AQP3 | CA3 1162/4885CA6 631/4885CA5A 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.