Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472935 | 0.89 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7474850 | 0.86 | CRHR1 (0.46) | CRHR1TLR8TLR7 | |
| SCHEMBL7478694 | 0.83 | CRHR1 (0.69) | CRHR1LIMK1 | |
| SCHEMBL5421029 | 0.81 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7484320 | 0.81 | CRHR1 (0.50) | CRHR1TLR8TLR7 | |
| SCHEMBL7472159 | 0.81 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7481208 | 0.79 | CRHR1 (0.48) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL7482439 | 0.78 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL7606978 | 0.78 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL7481401 | 0.78 | CRHR1 (0.65) | CRHR1TLR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225287-A1 | Substituted Arylpyrazines | YOON TAEYOUNG | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225287-A1 | Substituted Arylpyrazines | CRHR1, CRHR2, CRH | CRHR1 1/4885TLR8 1197/4885TLR7 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.