Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5534868 | 0.76 | FGFR1 (0.44) | FGFR1MKNK2HPGDALDH1A1LMNA | |
| SCHEMBL944619 | 0.70 | FGFR1 (0.51) | FGFR1MKNK2HPGDALDH1A1LMNA | |
| SCHEMBL19067514 | 0.70 | HCRTR1 (0.48) | KMT2ACHIAHTT | |
| SCHEMBL5534862 | 0.70 | FGFR1 (0.45) | FGFR1MKNK2HPGDALDH1A1LMNA | |
| SCHEMBL7854459 | 0.69 | DOT1L (0.48) | HPGDALDH1A1LMNAKMT2AUSP2 | |
| SCHEMBL8560640 | 0.68 | FGFR1 (0.59) | FGFR1MKNK2ALDH1A1TP53JAK2 | |
| SCHEMBL12516911 | 0.67 | KDM4C (0.53) | ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL31483721 | 0.67 | HTT (0.64) | HPGDALDH1A1KMT2AHTT | |
| SCHEMBL26417076 | 0.67 | HTT (0.64) | HPGDALDH1A1KMT2AHTT | |
| SCHEMBL10644638 | 0.66 | FGFR1 (1.00) | FGFR1HPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8221771-B2 | Formulations containing an immune response modifier | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-07-17 | — | — | US | disclosed |
| US-20070292456-A1 | Formulations Containing an Immune Response Modifier | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292456-A1 | Formulations Containing an Immune Response Modifier | IFNG, IRF3, ICOS | FGFR1 1524/4885MKNK2 2101/4885HPGD 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.