Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | GBA1 | P04062 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NSD2 | O96028 | 6/20 | 0.61 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.61 |
| ▸ | KDM1A | O60341 | 2/20 | 0.61 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 3/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280230 | 0.84 | LMNA (0.74) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL5527158 | 0.82 | ACHE (0.57) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14941071 | 0.81 | EHMT2 (0.75) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14941067 | 0.81 | EHMT2 (0.72) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14941385 | 0.80 | EHMT2 (0.76) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14941306 | 0.80 | EHMT2 (0.74) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14940912 | 0.80 | EHMT2 (0.74) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14585624 | 0.79 | LMNA (0.57) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL14941171 | 0.79 | DNMT3A (0.81) | LMNAMAPTHTTKMT2ANPSR1 | |
| SCHEMBL15714448 | 0.78 | EHMT2 (0.63) | LMNAMAPTHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| WO-2007071055-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | LMNA 1443/4885MAPT 1841/4885HTT 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.