SCHEMBL5535158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3168599	0.84	SIGMAR1 (0.66)	ACHEBACE1ALDH1A1OGAMCHR1
	SCHEMBL5547852	0.84	LMNA (0.61)	BCHEACHEBACE1ALDH1A1DRD2
	SCHEMBL2257602	0.83	SIGMAR1 (0.59)	ACHEBACE1ALDH1A1OGADRD4
	SCHEMBL5817187	0.82	ACHE (0.56)	BCHEACHEBACE1OGADRD2
	SCHEMBL2056135	0.76	ALDH1A1 (0.51)	ALDH1A1TSHROGA
	SCHEMBL2514685	0.76	HRH3 (0.52)	ACHEALDH1A1TSHRDRD2DRD3
	SCHEMBL12625981	0.75	ALDH1A1 (0.66)	BCHEACHEBACE1ALDH1A1TSHR
	SCHEMBL4350265	0.74	GRIN1 (0.72)	ALDH1A1
	SCHEMBL3149156	0.74	MCHR1 (0.53)	HRH3MCHR1SIGMAR1
	SCHEMBL6071351	0.74	MCHR1 (0.58)	ALDH1A1OGAHRH3MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.