Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL553580 | 0.82 | THRB (0.40) | THRBGAAMAPTTP53ALDH1A1 | |
| SCHEMBL6851614 | 0.82 | APP (0.39) | THRBCA12CA1CA4CA6 | |
| SCHEMBL15766019 | 0.82 | MAPT (0.41) | KMT2AGAAMAPTNPSR1MEN1 | |
| SCHEMBL3668740 | 0.78 | NR5A1 (0.45) | RAB9ANPC1KMT2AGAAMAPT | |
| SCHEMBL30848518 | 0.78 | NR5A1 (0.45) | RAB9ANPC1KMT2AGAAMAPT | |
| SCHEMBL15765999 | 0.76 | MAPT (0.38) | NPC1KMT2AGAAMAPTNPSR1 | |
| SCHEMBL29286602 | 0.75 | CA2 (0.37) | KMT2AGAAMAPTNPSR1MEN1 | |
| SCHEMBL2777243 | 0.75 | GAA (0.34) | THRBKMT2AGAANPSR1MEN1 | |
| SCHEMBL6927665 | 0.73 | THRB (0.62) | THRBCA12CA1CA4CA6 | |
| SCHEMBL28889443 | 0.73 | ELANE (0.38) | KMT2AGAAMAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020042483-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-04-11 | — | — | US | claimed |
| US-6657032-B2 | High refractive index and hydrophilic monomers, a crosslinker, an initiator and water | BAUSCH & LOMB INCORPORATED | 2003-12-02 | — | — | US | disclosed |
| US-20020042483-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-04-11 | — | — | US | disclosed |